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Study of innovative nanoformulations for bacterial eradication

Nanostructured lipid carriers and antibiotic nanospheres (NSs) will be prepared using high intensity ultrasound and high pressure homogenization. The NSs will be engineered on both composition and surface properties to be used against bacteria.

Objectius The student will acquire knowledge of how to prepare and characterize the obtained functional NSs using different techniques available in our lab. He/she will learn to work in a research group, think critically and solve problems in order to complete the scientific mission during the visiting period. Each student will be guided by an expert in the field of chemistry, microbiology, and nano(bio)technology to optimize the research process and maximize her/his learning experience. Furthermore, the applicant will have the opportunity to participate in national/international projects and scientific publications.
Tasques a realitzar / Característiques Literature research on the different strategies used to control bacterial growth and reduce the drug-resistant infections occurrence. Literature search on the currently available techniques for production of antibacterial and antibiofilm active antibiotic nanocarriers. Literature research on the techniques used to characterize the bulk properties and the added functionalities of the developed NSs. Experimental Research: Preparation of nanostructured antimicrobials by high intensity ultrasound or high pressure homogenization. Characterization of the NSs by dynamic light scattering, Z-potential evaluation, nanoparticle tracking analysis and Langmuir and Langmuir-Blodgett films. Evaluation of the NSs antibacterial activity towards common pathogens and their toxicity on human cells. Bachelor or Master Thesis writing Data processing and discussion of the obtained results in a scientific manner.
Tema Patologia i Farmacologia
Tipus Projecte
TFG/TFM TFG, TFM
Titulació 2012 - MASTER UNIVERSITARI EN OPTOMETRIA I CIÈNCIES DE LA VISIÓ, 2020 - GRAU EN ÒPTICA I OPTOMETRIA, 2022 - MASTER UNIVERSITARI EN OPTOMETRIA I CIÈNCIES DE LA VISIÓ
Paraules clau
Direction
Professor/a tzanko.tzanov
Nom del professor/a Tzanov, Tzanko kaloyanov
Email del professor/a TZANKO.TZANOV@UPC.EDU
Departament 713-EQ
Tipus de codirector/a UPC
Codirector/a kristina.ivanova
Nom del codirector/a Ivanova, Kristina dimitrova
Email del codirector/a KRISTINA.IVANOVA@UPC.EDU
Departament del codirector/a 713-EQ
Other data
Nombre d'estudiants 1
Càrrega de treball TFG 6ECTS = 150h / TFM 12ECTS = 300h
Requisits
Idioma del treball CA, ES, EN
Modality
Modalitat Universitat
Empresa
Options
Possibilitat de beca/finançament no
Confidencial (informatiu) no
Temàtica ambiental no
Ambit de cooperació no
Dates
Data de venciment 09/10/25 23:59
Continguts

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